Special instructions
How to prepare for your test
No fasting is required! Most medications do not interfere with HLA-B27 testing. However, let your lab know about any prescription or over-the-counter medicines you are taking. Drink plenty of water before your appointment. Being well-hydrated makes it easier to draw blood. Inform diagnosify of any autoimmune conditions, recent infections, or other relevant health concerns.
FAQ’s
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The HLA-B27 test checks for a specific genetic marker that is associated with autoimmune conditions such as ankylosing spondylitis and other inflammatory arthritis disorders.
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Doctors may order this test if you have symptoms such as chronic back pain, joint inflammation, or other signs of autoimmune disease. It helps support a diagnosis but cannot confirm a condition on its own.
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Positive: You carry the HLA-B27 gene, which may increase your risk of certain autoimmune conditions. Negative: You do not carry the HLA-B27 gene. This does not rule out autoimmune disease completely.